Police were on Sunday evening (November 7) called to the A30 near Ottery St Mary after a car was seen driving on the wrong side of the road.
Officers attending the A30 at Daisy Mount Cross shortly before 9pm arrested a 30-year-old woman from Somerset on suspicion of dangerous driving, and taking the wheel while above the legal drink-drive limit.
Devon and Cornwall Police said two vehicles crashed and the central reservation was hit.
Police said no one was reported injured.
The road was closed while the emergency services dealt with the crash and the vehicles were recovered.
A Devon and Cornwall Police spokesman said: “Police were called shortly before 9pm to the A30 at Daisy Mount Cross following reports of a vehicle travelling on the wrong carriageway.
“It was further reported that the vehicle had been in collision with another vehicle and the central reservation.
“The road was closed for a short time whilst emergency services attended the scene and the vehicles were recovered.
“No injuries were reported.”
He added: “A 30-year-old woman from Somerset was arrested on suspicion of dangerous driving and driving whilst alcohol above the limit.
“She has since been released under investigation pending further enquiries.”